https://ogma.newcastle.edu.au/vital/access/ /manager/Index ${session.getAttribute("locale")} 5 https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:37075 vs 21.4 (5.1) cm³; P = 0.027) despite no significant difference in body weight. Despite having a smaller TRV, there was no significant difference in eGFR between Indigenous and Non-indigenous neonates (47.8 [43.2-50.4] vs 46.2 [42.6-53.3] ml/min per 1.73 m²; P = 0.986). These infants achieve similar eGFR through hyperfiltration, which likely increases their future risk of CKD. There was no difference in microalbumin-creatinine ratio. Female Indigenous neonates, however, had significantly smaller TRV compared with Indigenous male neonates (15.9 (3.6) vs 20.6 (3.6) cm³; P = 0.006), despite no difference in eGFR, birth weight, gestational age, and weight at term corrected. Conclusion: The difference in TRV is likely to be an important risk factor for the difference in morbidity and mortality from renal disease reported between male and female Indigenous adults.]]> Wed 15 Dec 2021 16:07:38 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:18831 Wed 11 Apr 2018 09:37:04 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:38156 Wed 04 Aug 2021 18:23:49 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:49044 37 weeks) admitted to and treated in the neonatal unit at the Townsville University Hospital between March 2015 and March 2020. Neonatal sepsis was confirmed with positive neonatal blood culture. Data on neonatal birth/stay and maternal pregnancy were collected from the electronic medical records and neonatal database. Results: Data from 737 neonates who were admitted for treatment of EONS were analysed. Sixty % (426) reported maternal intrapartum fever, with 1.1% (5) of neonates developing blood culture-proven sepsis. Forty % did not report intrapartum fever (311), with 3% (9) of neonates developing sepsis. As such, the sensitivity and specificity of maternal fever are 1.14% and 97%, respectively. The positive predictive value was 35.7%, and the negative predictive value was 40.1%. Fourteen neonates developed EONS, and all of them were symptomatic. Seventy-eight % (334/426) of the women in the febrile group received epidural analgesia compared to 5% (16/311) in the afebrile group. Of the 95 neonates born to women with chorioamnionitis, one (1.0%) of the neonates born to women with chorioamnionitis developed sepsis. Conclusions: Intrapartum maternal fever is an unreliable predictor for EONS and leads to unnecessary antibiotic treatment. Symptoms in the neonate are a more reliable indicator of an ill neonate with blood culture-proven sepsis.]]> Wed 03 May 2023 13:55:00 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:36685 in utero and early life insults and the development of chronic illness remains to be fully understood, but there is increasing data to indicate that microvasculature pathology plays an important mechanistic role. Currently available data indicate that retinal microvasculature changes are detectable in children as young as six years of age, however, there are no data for younger children. We present retinal microvasculature measurement from the first two years of life. Retinal images suitable for analysis were available from 18 infants in our proof-of-concept study. The mean and standard deviation (SD)for birth weight and gestation was 3410 (384)g and 39.1(1.4)weeks, respectively. Retinal vessel calibres were summarized as the mean(SD)central retinal arteriolar equivalent (CRAE)at six months of age was 156 (32)µm, increased to 175 (75)µm by 12 months and a slightly declined by 24 months of age to 168 (50)µm. In a similar pattern, mean(SD)central retinal venular equivalent (CRVE)at six months was 211 (19)µm, increased to 238 (25)µm by 12 months of age followed by a slight decline at 24 months of age to 222 (36)µm. The arterio-venous ratio and tortuosity index remained the same at 6, 12 and 24 months. Findings from this study could help future investigators better understand early microvasculature changes and adaptation that occur early in life.]]> Tue 23 Jun 2020 17:02:42 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:39922 Thu 30 Jun 2022 11:55:31 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:36997 Thu 30 Jul 2020 16:38:14 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:34951 Thu 09 Dec 2021 11:04:52 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:30441 Sat 24 Mar 2018 07:38:10 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:30848 Sat 24 Mar 2018 07:33:54 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:22880 Sat 24 Mar 2018 07:12:59 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:34950 Mon 27 May 2019 12:39:55 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:49512 Fri 19 May 2023 17:16:55 AEST ]]>